1. Identification of botanical extracts which alter the pathophysiological mechanisms related to the development of insulin resistance.
2. Development of new methods to rapidly screen for effectiveness of bioactive constituents of botanicals in insulin action.
3. Identification of targets (e.g., molecular, cellular, organ) and mechanisms of action of botanical test materials and bioactive constituents.
4. Assessment of synergy and/or antagonism among bioactive constituents of botanical preparations and their role in insulin signaling.
5. Studies of the role of botanicals as regulators of genetic pathways or epigenetic events associated with risk of developing metabolic syndrome, obesity and Type 2 diabetes, or co-morbidities associated with these conditions (i.e. hypertension, dyslipidemia, inflammation).
6. Studies on the absorption and metabolism of botanical bioactive compounds.

Click here for more information, or to submit your application